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New York, NY (Sports Network) - New York Jets wide receiver Santonio Holmes will miss the remainder of the season with a Lisfranc injury in his left foot, according to a report in the New York Daily News.

Holmes suffered the injury during the fourth quarter of Sunday's 34-0 loss to the San Francisco 49ers after making a catch. He immediately fell to the ground without being contacted and let go of the ball, which 49ers cornerback Carlos Rogers promptly returned for a 51-yard touchdown

The seven-year veteran was unable to put any weight on his left leg and was carted off the field.

X-rays of the foot were negative, but the Daily News reported an MRI on the injury by foot specialist Robert Anderson in North Carolina discovered the extent of the injury.

Holmes recorded four catches for 29 yards before exiting Sunday, and has 20 receptions for 272 yards and a touchdown this season.

This would be the second significant injury for the Jets this season as the team already lost superstar cornerback Darrelle Revis for the season due to an ACL injury.