4th quarter-The Bills are one quarter away from their first four game winning streak since 2008. Phil Dawson adds a 47 yard field goal and the Bills lead has been cut to 8, 24-16 with just 12 seconds gone in the fourth quarter. San Francisco has the wind at its back in this quarter.

Tyrod Taylor finds Charles Clay for a 14 yard gain and a first down. Taylor with an impressive escape to make something out of nothing.

Taylor with a run for 21 yards. He now has 68 on the day. His running ability is amazing and he often makes something out of nothing. His running helped set up LeSean McCoy's 18 yard touchdown. Bills now lead 31-16. 10:53 showing on the game clock. McCoy now with 140 yards on the day and 3 TD's. Impressive day and its not over yet.

Nickell Robey-Coleman forces a fumble on the kickoff. Jonathan Meeks recovers and the Bills are in business at the San Francisco 27 yard line. LeSean McCoy is interfered with as the Bills go right for the end zone. McCoy has tied a career high with 3 touchdowns.

Taylor hits Robert Woods for the 5 yard touchdown. The Bills lead it 38-16 with 10:32 to go in the fourth quarter. With that touchdown Taylor passes Rob Johnson with 28 career touchdown passes and moves into 9th place in franchise history.

Lorenzo Alexander gets a sack forces a fumble but the 49ers recover the ball. 12 yard loss on the play.

EJ Manuel has come into the game at quarterback for the Bills. Reggie Bush is also in at running back.

Mike Gillislee gets into the act with a 44 yard touchdown run. The shellacking is on as the Bills lead 45-16 with 5:40 left in the fourth quarter.

The Bills cough it up and San Francisco recovers. Its the second time today that the 49ers have recovered a Buffalo fumble. Adolphus Washington with the sack for a 7 yard loss. The Bills stop the 49ers on downsand take over at their own 11 yard line. Robey-Coleman and Darby with a couple of nice pass break ups on the series.

All the Bills are waiting for is the clock to strike 0:00. They have won 4 straight for the first time since 2008. Once again LeSean McCoy and the running game lead the way.

3rd quarter: Before the third quarter starts the Bills get good news. LeSeaon McCoy has been cleared to return. McCoy is back in the game and the Bills sent out this statistic. LeSean McCoy is the first NFL running back to rush for 100 yards in the first half of consecutive games since Cincinnati’s Jeremy Hill on December 14 and 22 in 2014. The Bills first drive of the half went nowhere. It is windy here at the stadium and that could become more of factor as the game goes along. The Bills lead by four and would certainly like to add to it. It appears unless the wind shifts that San Francisco will have it at their back in the fourth quarter.

Colton Schmidt with a beautiful punt for the Bills. The 49ers drive will start at their own 5 yard line. Jerry Hughes has Kaepernick in his grasp in the end zone but can't keep him there for the safety. The drive ends with a punt a few plays later.

Both defenses have taken over here in the third quarter. With 4:40 left in the quarter Preston Brown stuffs Mike Davis on 4th and one and the Bills take over on downs. Nick O'Leary with a catch for a gain of 23 yards. Great to see the tight end so involved in the game for the Bills. On the next play Tyrod Taylor hits Justin Hunter for the 30 yard touchdown and the Bills take a 24 to 13 lead with 2:34 left in the third quarter. The third quarter ends with San Francisco facing a 3rd and 8 at the Buffalo 29 yard line. The Bills lead by 11, 24-13.

2nd Quarter: San Francisco regains the lead. There appeared to be a miscommunication in the Bills backfield and Kaepernick found a wide open Torrey Smith for the 53 yard touchdown and a 10-7 lead with the quarter one minute and four seconds old.

Taylor completes another pass to Charles Clay. I always like seeing the tight end heavily involved in the passing game. LeSean McCoy breaks off a 38 yard run. And now Nick O'lear gets a catch so no matter who is playing the position the Bills are really using the tight end in the passing game. McCoy goes 12 yards for the touchdown after taking the direct snap and the Bills retake the lead 14-10 with 10:18 to go in the second quarter.

For the most part San Francisco has been able to move the ball pretty well and consistently against the Bills defense so far today. Lorenzo Alexander 3rd down pass and Phil Dawson kicks a 48 yard field goal. Bills lead is cut to one, 14-13.

With the clocking ticking toward the 2 minute warning LeSean McCoy gains 24 yards on 3rd and 20. That run also put him over 100 yards for the game.

From the Bills: With 83 yards passing today, Tyrod Taylor has passed the 4,000-yard mark for passing yards with the Buffalo Bills. He accomplished the feat in his 20th career game in Buffalo – the fourth fastest quarterback to reach this milestone (Drew Bledsoe – 15, Jim Kelly – 18, Doug Flutie – 19).

With the Bills driving in the final minute of the half McCoy caught a pass from Tyrod Taylor. McCoy was down on the field for a few minutes before heading to the Buffalo bench with the trainers.

The Bills drive stalls and Dan Carpenter comes on to try the 40 yard field goal. Its good and the Bills lead 17 to 13.

McCoy was up and on the sidelines and planting his foot on the turf.

The Bills lead by four, 17-13 at the half.

1st Quarter: On the Bills first posession they fumbled and the 49ers recovered at the Buffalo 28 yard line. The defense was on top of Tyrod Taylor as he was trying to hand the ball off. The 49ers used their first time out of the half on the ensuing drive as they face a 3rd and 22 from the Buffalo 26 yard line. San Francisco settles for the field goal try and it is good by Phil Dawson from 33 yards out. San Francisco takes the early lead off the turnover, 3-0. Colin Kaepernick overthrew one wide receiver on the first drive, a good throw there and it was 6 and on the second drive another throw was too long and if not a TD might have been awfully close.

The Bills answer with a four yard touchdown run from LeSean McCoy and take a 7-to-3 with 14 seconds left in the first quarter. 11 plays 75 yards for 5:29 seconds on the drive. Taylor had Clay open in the end zone but didn't see him and was sacked but on the next play found Clay for a fist down inside the five. The Bills got a generous spot I thought but they took advantage of it and took the lead.

The Bills are riding a 3 game winning streak as the San Francisco 49ers come to Orchard Park. The Bills haven't won 4 straight since 2008.

Here the Bills players who are not active for the game

Cardale Jones

Ikard Jones

Seantrel Henderson

Patrick Lewis

Cyrus Kouandjo

Gerald Christian

Marcell Dareus

Here are the inactives for San Francisco

Christian Ponder

Jimmie Ward

Jaquiski Tartt

Tony Jerod-Eddie

John Theus

Blake Bell

Taylor Hart

Corbin Bryan starts at nose tackle for the Bills.

Adolphus Washington starts at defensive end.

Rashard Robinson starts at right cornerback for San Francisco.